Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556280 | 0.86 | PIK3CD (0.35) | CA1CA2CA4KMT2ABRD4 | |
| Hydrochloric Acid SCHEMBL10768662 | 0.84 | PIK3CD (0.34) | CA1CA2CA4KMT2ABRD4 | |
| SCHEMBL18469064 | 0.79 | RAB9A (0.35) | CA1CA2CA4KMT2APIK3CD | |
| SCHEMBL19207703 | 0.77 | BRD4 (0.37) | KMT2ABRD4BRD2CHRNB2CHRNB4 | |
| SCHEMBL4181392 | 0.72 | — | — | |
| SCHEMBL2021592 | 0.72 | — | — | |
| SCHEMBL10182573 | 0.72 | — | — | |
| SCHEMBL22527291 | 0.71 | DRD4 (0.43) | BRD4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13294084 | 0.70 | BRD4 (0.52) | CA1CA2CA4KMT2ABRD4 | |
| SCHEMBL261177 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2907824-B1 | ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO CO LTD (JP) | 2018-04-11 | — | — | EP | disclosed |