SCHEMBL2004120

SCHEMBL2004120

CC(C)[C@H](OCc1ccccc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 7/20 0.67
SLC1A1 P43005 7/20 0.67
SLC1A3 P43003 6/20 0.67
KMT2A Q03164 2/20 0.67
MEN1 O00255 1/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2D6 P10635 1/20 0.67
CYP2C9 P11712 1/20 0.67
CYP2C19 P33261 1/20 0.67
ALDH1A1 P00352 3/20 0.48
TSHR P16473 1/20 0.44
SLC15A1 P46059 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2004125 1.00 SLC1A2 (0.67) SLC1A2SLC1A1SLC1A3KMT2AMEN1
SCHEMBL2000767 0.89 SLC1A2 (0.63) SLC1A2SLC1A1SLC1A3KMT2AMEN1
SCHEMBL418322 0.88 SLC1A3 (0.76) SLC1A2SLC1A1SLC1A3KMT2AMEN1
SCHEMBL1953602 0.88 SLC1A3 (0.76) SLC1A2SLC1A1SLC1A3KMT2AMEN1
SCHEMBL852209 0.88 SLC1A3 (0.76) SLC1A2SLC1A1SLC1A3KMT2AMEN1
SCHEMBL8840019 0.87 SLC1A2 (0.65) SLC1A2SLC1A1SLC1A3KMT2AMEN1
Water SCHEMBL30419716 0.86 SLC1A3 (0.73) SLC1A2SLC1A1SLC1A3KMT2AMEN1
SCHEMBL828782 0.86 SLC1A3 (0.54) SLC1A2SLC1A1SLC1A3KMT2AMEN1
SCHEMBL824885 0.86 SLC1A3 (0.54) SLC1A2SLC1A1SLC1A3KMT2AMEN1
SCHEMBL6062626 0.85 SLC1A3 (0.51) SLC1A2SLC1A1SLC1A3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11147788-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2021-10-19 US disclosed
US-10934244-B2 Compounds for use in treating neuromuscular disorders NMD PHARMA A/S (DK) 2021-03-02 US disclosed
US-10385028-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2019-08-20 US disclosed
US-20190183863-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20190185437-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS (DK) 2019-06-20 US disclosed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS (DK) 2019-06-20 US disclosed
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US disclosed
US-20180099920-A1 COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS NMD PHARMA APS (DK) 2018-04-12 US disclosed
US-20180099920-A1 COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS NMD PHARMA APS (DK) 2018-04-12 US disclosed
US-7960420-B2 Diazonamide analogs with improved solubility JOYANT PHARMACEUTICALS, INC (US) 2011-06-14 US disclosed
US-7960420-B2 Diazonamide analogs with improved solubility JOYANT PHARMACEUTICALS, INC (US) 2011-06-14 US disclosed
WO-2009086170-A1 DIAZONAMIDE ANALOGS WITH IMPROVED SOLUBILITY JOYANT PHARMACEUTICALS, INC. (US) 2009-07-09 WO disclosed
US-20090163446-A1 DIAZONAMIDE ANALOGS WITH IMPROVED SOLUBILITY JOYANT PHARMACEUTICALS, INC. 2009-06-25 US disclosed
US-20090163446-A1 DIAZONAMIDE ANALOGS WITH IMPROVED SOLUBILITY JOYANT PHARMACEUTICALS, INC. 2009-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730714-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 SLC1A2 125/4885SLC1A1 85/4885SLC1A3 107/4885
US-10934244-B2 Compounds for use in treating neuromuscular disorders CPT1B, CLCN2, TNNC1 SLC1A2 68/4885SLC1A1 71/4885SLC1A3 81/4885
US-20090163446-A1 DIAZONAMIDE ANALOGS WITH IMPROVED SOLUBILITY PKD1, PKD2, GLS SLC1A2 1270/4885SLC1A1 924/4885SLC1A3 347/4885
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 SLC1A2 125/4885SLC1A1 85/4885SLC1A3 107/4885
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders CPT1B, CLCN2, CACNB1 SLC1A2 80/4885SLC1A1 35/4885SLC1A3 33/4885
US-20180099920-A1 COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS CPT1B, CLCN2, TNNC1 SLC1A2 68/4885SLC1A1 71/4885SLC1A3 81/4885
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 SLC1A2 125/4885SLC1A1 85/4885SLC1A3 107/4885
US-11147788-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 SLC1A2 125/4885SLC1A1 85/4885SLC1A3 107/4885
US-10385028-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 SLC1A2 125/4885SLC1A1 85/4885SLC1A3 107/4885
US-20190183863-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 SLC1A2 125/4885SLC1A1 85/4885SLC1A3 107/4885
US-20190185437-A1 Compounds For The Treatment Of Neuromuscular Disorders CLCN2, SCN1B, CACNB1 SLC1A2 56/4885SLC1A1 37/4885SLC1A3 40/4885
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 SLC1A2 125/4885SLC1A1 85/4885SLC1A3 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.