SCHEMBL20041236

SCHEMBL20041236

CCC1CCN(C2CN(C)C2)C1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.35
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22703760 0.90 NCF1 (0.39) NCF1
SCHEMBL22703786 0.89 NCF1 (0.37) NCF1
SCHEMBL12818575 0.86 NCF1 (0.43) NCF1DPP4
SCHEMBL12717710 0.86 NCF1 (0.43) NCF1DPP4
SCHEMBL25972140 0.85 DPP4 (0.36) NCF1DPP4
SCHEMBL24294204 0.82
SCHEMBL18664007 0.81 DPP4 (0.41) DPP4
SCHEMBL27423164 0.81 DPP4 (0.41) DPP4
SCHEMBL11000044 0.81 DPP4 (0.45) DPP4
SCHEMBL12835 0.80 KCNH2 (0.33) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3971176-A1 AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE Hinova Pharmaceuticals Inc. (CN) 2022-03-23 EP disclosed
WO-2020233512-A1 AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE 成都海创药业有限公司 (CN) 2020-11-26 WO disclosed
EP-3140297-B1 PYRROLIDINE GPR40 MODULATORS FOR THE TREATMENT OF DISEASES SUCH AS DIABETES BRISTOL MYERS SQUIBB CO (US) 2018-04-11 EP disclosed