Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041397 | 0.88 | P2RX4 (0.36) | GAAMEN1KMT2AKDM4ETP53 | |
| SCHEMBL20041457 | 0.73 | GAA (0.40) | GAAMEN1KMT2AKDM4ETP53 | |
| SCHEMBL16922779 | 0.72 | GAA (0.39) | GAAMEN1KMT2AKDM4ETP53 | |
| SCHEMBL20041447 | 0.71 | KMT2A (0.38) | GAAMEN1KMT2AKDM4ETP53 | |
| SCHEMBL15489943 | 0.70 | P2RX4 (0.44) | GAAKMT2AP2RX4MAPTSMN1; SMN2 | |
| SCHEMBL12433669 | 0.69 | ALDH1A1 (0.39) | GAAKDM4ETP53HTTP2RX4 | |
| SCHEMBL11978697 | 0.69 | P2RX4 (0.43) | GAAKMT2AKDM4ETP53HTT | |
| SCHEMBL21765588 | 0.68 | GAA (0.45) | GAAMEN1KMT2AKDM4ETP53 | |
| SCHEMBL11414159 | 0.67 | TDP1 (0.48) | GAAMEN1KMT2AKDM4ETP53 | |
| SCHEMBL12841614 | 0.66 | KDM4E (0.47) | GAAMEN1KMT2AKDM4EP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |