Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17507240 | 0.83 | NPC1 (0.51) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL20041411 | 0.82 | TOP2A (0.36) | NPC1RAB9ATOP2AALDH1A1HPGD | |
| SCHEMBL17507251 | 0.81 | NPC1 (0.50) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL20041722 | 0.81 | NPC1 (0.47) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL20041677 | 0.80 | NPC1 (0.45) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL20041658 | 0.79 | NPC1 (0.48) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL17507388 | 0.78 | NPC1 (0.46) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL29697227 | 0.78 | NPC1 (0.51) | NPC1RAB9ATOP2AALDH1A1HPGD | |
| SCHEMBL20561245 | 0.78 | NPC1 (0.51) | NPC1RAB9ATOP2AALDH1A1HPGD | |
| SCHEMBL20041423 | 0.78 | NPC1 (0.42) | NPC1RAB9AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |