SCHEMBL29697227

SCHEMBL29697227

c1ccc2c(c1)[nH]c1cc3nc4oc5ccccc5n4c3cc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
AHR P35869 1/20 0.42
TOP2A P11388 1/20 0.40
GABRP O00591 7/20 0.37
GABRD O14764 7/20 0.37
GABRA1 P14867 7/20 0.37
GABRB1 P18505 7/20 0.37
GABRG2 P18507 7/20 0.37
GABRB3 P28472 7/20 0.37
GABRA5 P31644 7/20 0.37
GABRA3 P34903 7/20 0.37
GABRA2 P47869 7/20 0.37
GABRB2 P47870 7/20 0.37
GABRA4 P48169 7/20 0.37
GABRE P78334 7/20 0.37
GABRA6 Q16445 7/20 0.37
GABRG1 Q8N1C3 7/20 0.37
GABRG3 Q99928 7/20 0.37
GABRQ Q9UN88 7/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20561245 1.00 NPC1 (0.51) NPC1RAB9AAHRTOP2AGABRP
SCHEMBL23903104 0.81 NPC1 (0.54) NPC1RAB9AAHRTOP2AGABRP
SCHEMBL20041739 0.78 NPC1 (0.44) NPC1RAB9AAHRTOP2AGABRP
SCHEMBL23902934 0.76 NPC1 (0.51) NPC1RAB9AGABRA1GABRG2GABRB3
SCHEMBL18934281 0.76 AHR (0.47) AHRTOP2AGABRPGABRDGABRA1
SCHEMBL23045967 0.73 NPC1 (0.53) NPC1RAB9AALDH1A1HSD17B10KDM4E
SCHEMBL17491659 0.72 NPC1 (0.66) NPC1RAB9AGABRPGABRDGABRA1
SCHEMBL18934858 0.71 AHR (0.41) AHRTOP2AGABRPGABRDGABRA1
SCHEMBL18934277 0.70 AHR (0.47) AHRTOP2AGABRPGABRDGABRA1
SCHEMBL20041633 0.70 NPC1 (0.51) NPC1RAB9AALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989192-A Organic electroluminescent material and device 环球展览公司 2022-09-02 CN disclosed
CN-108948044-B Organic electroluminescent material and device 环球展览公司 2022-07-26 CN disclosed