Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308609 | 0.77 | ATM (0.55) | MAPTSMN1; SMN2L3MBTL1ATMHPGD | |
| SCHEMBL8686358 | 0.74 | MAPT (0.45) | MAPTSMN1; SMN2L3MBTL1ATMHPGD | |
| SCHEMBL25743006 | 0.73 | ATM (0.61) | MAPTSMN1; SMN2L3MBTL1ATMNPC1 | |
| SCHEMBL26372467 | 0.71 | PGR (0.43) | MAPTATMHPGDRAB9AALDH1A1 | |
| SCHEMBL19356153 | 0.71 | PGR (0.43) | MAPTATMHPGDRAB9AALDH1A1 | |
| SCHEMBL19098526 | 0.69 | LMNA (0.46) | MAPTSMN1; SMN2L3MBTL1ATMRAB9A | |
| SCHEMBL14180869 | 0.69 | LMNA (0.47) | MAPTSMN1; SMN2ATMHPGDNPC1 | |
| SCHEMBL19066352 | 0.68 | ATM (0.59) | MAPTSMN1; SMN2L3MBTL1ATMNPC1 | |
| SCHEMBL19066350 | 0.68 | ATM (0.59) | MAPTSMN1; SMN2L3MBTL1ATMNPC1 | |
| SCHEMBL5419606 | 0.68 | MAPT (0.45) | MAPTSMN1; SMN2L3MBTL1ATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305783-A1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | Freie Universität Berlin (DE) | 2018-04-11 | — | — | EP | disclosed |