Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | STAT5B | P51692 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936153 | 0.81 | ALDH1A1 (0.41) | NPSR1ALDH1A1SMN1; SMN2KDM4ECA12 | |
| SCHEMBL8786752 | 0.78 | CA12 (0.39) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL10000161 | 0.76 | NPSR1 (0.46) | NPSR1STAT5BALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8936016 | 0.73 | HTT (0.43) | ALDH1A1POLBSMN1; SMN2TSHRKMT2A | |
| SCHEMBL22213898 | 0.70 | NPSR1 (0.45) | NPSR1STAT5BALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL13343501 | 0.69 | KMT2A (0.50) | NPSR1ALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL17950597 | 0.69 | NPSR1 (0.48) | NPSR1STAT5BALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL23990643 | 0.68 | CA12 (0.46) | NPSR1STAT5BALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL25745155 | 0.68 | CA9 (0.46) | STAT5BALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL30281403 | 0.67 | CA12 (0.49) | ALDH1A1TSHRKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |