SCHEMBL20041811

SCHEMBL20041811

O=C(O)c1nonc1NCN1C=CNN1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STAT5B P51692 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11888589 0.69 STAT5B (1.00) STAT5B
SCHEMBL22096025 0.69 STAT5B (0.67) STAT5B
SCHEMBL20041808 0.69 STAT5B (0.64) STAT5B
SCHEMBL14399057 0.68 STAT5B (0.52) STAT5B
SCHEMBL22096008 0.65 ALDH1A1 (0.67) STAT5B
SCHEMBL22096016 0.64 STAT5B (0.81) STAT5B
SCHEMBL22096022 0.63 STAT5B (0.81) STAT5B
SCHEMBL22096026 0.62 STAT5B (1.00) STAT5B
SCHEMBL22096030 0.61 STAT5B (0.82) STAT5B
SCHEMBL20041805 0.59 STAT5B (0.45) STAT5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3305783-A1 NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER Freie Universität Berlin (DE) 2018-04-11 EP disclosed