Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559384 | 1.00 | DDB1 (0.44) | DDB1CRBNMAP2K1GAAALDH1A1 | |
| SCHEMBL19559433 | 0.99 | DDB1 (0.43) | DDB1CRBNMAP2K1GAAALDH1A1 | |
| SCHEMBL18590511 | 0.83 | SMN1; SMN2 (0.40) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19862623 | 0.83 | SMN1; SMN2 (0.40) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18590513 | 0.82 | POLB (0.42) | GAASMN1; SMN2KMT2ANPC1PDE7A | |
| SCHEMBL19862626 | 0.82 | POLB (0.42) | GAASMN1; SMN2KMT2ANPC1PDE7A | |
| SCHEMBL26976633 | 0.80 | DDB1 (0.48) | DDB1CRBNMAP2K1GAAALDH1A1 | |
| SCHEMBL19559402 | 0.80 | DDB1 (0.48) | DDB1CRBNMAP2K1GAAALDH1A1 | |
| SCHEMBL8642136 | 0.71 | HPSE (0.41) | DDB1CRBNGAAALDH1A1TSHR | |
| SCHEMBL22804573 | 0.70 | MEN1 (0.46) | GAAALDH1A1SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305763-A1 | DEUTERATED OR ISOTOPICALLY LABELED UREA DERIVATIVES OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF USEFUL AS FPRL-1 AGONISTS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |