Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15845875 | 0.82 | MAPT (0.39) | MAPTKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL15845865 | 0.82 | MAPT (0.39) | MAPTKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL15845863 | 0.82 | MAPT (0.39) | MAPTKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL13838711 | 0.76 | MEN1 (0.40) | MAPTKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL18895798 | 0.76 | CFTR (0.55) | MAPTKDM4ECYP2C19KMT2AMAPK1 | |
| SCHEMBL20052481 | 0.76 | L3MBTL1 (0.44) | MAPTKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL20052480 | 0.76 | L3MBTL1 (0.44) | MAPTKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL6118430 | 0.75 | L3MBTL1 (0.44) | MAPTKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL12025132 | 0.72 | L3MBTL1 (0.56) | MAPTKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL178010 | 0.72 | CYP3A4 (0.50) | MAPTKDM4ERAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099937-A1 | NOVEL ARYL-CYANOGUANIDINE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099937-A1 | NOVEL ARYL-CYANOGUANIDINE COMPOUNDS | SMYD2, SETD2, SMYD3 | MAPT 1508/4885KDM4E 115/4885RAB9A 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.