Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21443295 | 0.84 | CA1 (0.42) | MAPTKDM4EHSD17B10CASP1KMT2A | |
| SCHEMBL20052481 | 0.82 | L3MBTL1 (0.44) | L3MBTL1RAB9AMAPTNPSR1KDM4E | |
| SCHEMBL10451549 | 0.81 | MEN1 (0.53) | L3MBTL1RAB9AMAPTNPSR1HTR2A | |
| SCHEMBL6118430 | 0.78 | L3MBTL1 (0.44) | L3MBTL1RAB9AMAPTNPSR1HTR2A | |
| SCHEMBL30313140 | 0.78 | CYP3A4 (0.50) | L3MBTL1RAB9AMAPTNPSR1KDM4E | |
| SCHEMBL178010 | 0.78 | CYP3A4 (0.50) | L3MBTL1RAB9AMAPTNPSR1KDM4E | |
| SCHEMBL28407737 | 0.77 | L3MBTL1 (0.45) | L3MBTL1RAB9AMAPTNPSR1HTR2A | |
| SCHEMBL15845875 | 0.76 | MAPT (0.39) | L3MBTL1RAB9AMAPTNPSR1HTR2A | |
| SCHEMBL15845863 | 0.76 | MAPT (0.39) | L3MBTL1RAB9AMAPTNPSR1HTR2A | |
| SCHEMBL20042059 | 0.76 | MAPT (0.39) | L3MBTL1RAB9AMAPTNPSR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49698-E1 | Substituted dihydroquinazolines | AIC246 AG & CO. KG (DE) | 2023-10-17 | — | — | US | disclosed |
| US-RE46791-E1 | Substituted dihydroquinazolines | AICURIS ANTI-INFECTIVE CURES GMBH (DE) | 2018-04-17 | — | — | US | disclosed |