Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 12/20 | 0.66 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18153282 | 0.99 | ROCK2 (0.64) | ROCK2ROCK1ABCG2LMNAMAPT | |
| SCHEMBL20042168 | 0.87 | ROCK2 (0.68) | ROCK2ROCK1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL18153316 | 0.86 | ROCK2 (0.67) | ROCK2ROCK1LMNAMAPT | |
| SCHEMBL18153406 | 0.83 | ROCK2 (0.62) | ROCK2ROCK1ABCG2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL23197968 | 0.82 | ROCK2 (0.61) | ROCK2ROCK1ABCG2LMNAMAPT | |
| SCHEMBL18162449 | 0.82 | ABCG2 (0.47) | ROCK2ROCK1ABCG2LMNAMAPT | |
| SCHEMBL20774647 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL20042169 | 0.77 | ABCG2 (0.47) | ROCK2ROCK1ABCG2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL18153287 | 0.77 | ABCG2 (0.47) | ROCK2ROCK1ABCG2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL18153427 | 0.75 | ROCK1 (0.56) | ROCK2ROCK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099952-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099952-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | HAVCR2, MAVS, HCCS | ROCK2 2833/4885ROCK1 2890/4885ABCG2 4610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.