Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | YES1 | P07947 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042473 | 0.91 | PIK3CA (0.40) | MAPK1DDR1PIK3CAMAPK8MAPK9 | |
| SCHEMBL20042476 | 0.90 | MAPK1 (0.40) | CYP1A2CYP2C19RAB9AMAPK1DDR1 | |
| SCHEMBL20042456 | 0.90 | CYP1A2 (0.33) | CYP1A2CYP2C19RAB9AMAPK1DDR1 | |
| SCHEMBL20042474 | 0.89 | CYP1A2 (0.33) | CYP1A2CYP2C19RAB9AMAPK1DDR1 | |
| SCHEMBL20042475 | 0.89 | RORC (0.34) | CYP1A2CYP2C19RAB9AMAPK1DDR1 | |
| SCHEMBL20042377 | 0.88 | RORC (0.34) | MAPK1DDR1PIK3CAMAPK8MAPK9 | |
| SCHEMBL30051769 | 0.88 | RORC (0.34) | MAPK1DDR1PIK3CAMAPK8MAPK9 | |
| SCHEMBL31534713 | 0.87 | JAK1 (0.38) | DDR1PIK3CARORC | |
| SCHEMBL17967731 | 0.87 | JAK1 (0.38) | DDR1PIK3CARORC | |
| SCHEMBL20042457 | 0.86 | MAPK1 (0.35) | MAPK1DDR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | disclosed |
| EP-3523299-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-20200048246-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| WO-2018065292-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048246-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | EPHX2, CYP8B1, CYP1B1 | CYP1A2 5/4885CYP2C19 126/4885RAB9A 467/4885 |
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | EPHX2, CYP8B1, CYP1B1 | CYP1A2 5/4885CYP2C19 126/4885RAB9A 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.