Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 11/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 10/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 10/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 10/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042377 | 0.92 | RORC (0.34) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL30051769 | 0.92 | RORC (0.34) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL17967731 | 0.92 | JAK1 (0.38) | PIK3CADDR1 | |
| SCHEMBL31534713 | 0.92 | JAK1 (0.38) | PIK3CADDR1 | |
| SCHEMBL20042460 | 0.91 | CYP1A2 (0.34) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL20042476 | 0.90 | MAPK1 (0.40) | PIK3CAMAPK1ABL1DDR1 | |
| SCHEMBL20042456 | 0.90 | CYP1A2 (0.33) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL20042457 | 0.90 | MAPK1 (0.35) | MAPK1ABL1DDR1 | |
| SCHEMBL20042474 | 0.90 | CYP1A2 (0.33) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL20042475 | 0.90 | RORC (0.34) | PIK3CAMAPK1MAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | disclosed |
| EP-3523299-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-20200048246-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| WO-2018065292-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048246-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | EPHX2, CYP8B1, CYP1B1 | PIK3CA 1365/4885MAPK1 2882/4885MAPK8 4223/4885 |
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | EPHX2, CYP8B1, CYP1B1 | PIK3CA 1365/4885MAPK1 2882/4885MAPK8 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.