Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042774 | 0.75 | TUBB3 (0.34) | HTR2C | |
| SCHEMBL20042648 | 0.71 | CHRM3 (0.51) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL2806533 | 0.65 | LRRK2 (0.38) | — | |
| SCHEMBL21035571 | 0.64 | HTR2C (0.47) | HTR2AHTR2CHTR2BPDE10ACHRM3 | |
| SCHEMBL20042975 | 0.63 | CHRM3 (0.42) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL18649181 | 0.62 | LMNA (0.50) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL22344966 | 0.62 | HTR2C (0.32) | HTR2CHTR2B | |
| SCHEMBL14483195 | 0.61 | HTR2C (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL18649253 | 0.61 | LMNA (0.48) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL29974030 | 0.61 | HTR2C (0.34) | HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |