Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042746 | 1.00 | MTOR (0.41) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL31614795 | 0.81 | MTOR (0.47) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL20042670 | 0.81 | MTOR (0.47) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL29182037 | 0.80 | MTOR (0.39) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL30118094 | 0.80 | MTOR (0.39) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL24837469 | 0.80 | MTOR (0.39) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL27191286 | 0.80 | MTOR (0.39) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL20608461 | 0.78 | C5AR1 (0.39) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL31016562 | 0.76 | C5AR1 (0.39) | MTORGPR119PARP1TNKS2PARP2 | |
| SCHEMBL20042662 | 0.76 | C5AR1 (0.39) | MTORGPR119PARP1TNKS2PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |