Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27270438 | 0.85 | MEN1 (0.37) | MEN1KMT2AALDH1A1MAP4K4SCN4A | |
| SCHEMBL20042845 | 0.84 | MEN1 (0.36) | MEN1KMT2AALDH1A1GPR119MAP4K4 | |
| SCHEMBL20042828 | 0.83 | CHRM3 (0.40) | PDE8BALDH1A1CHRM3 | |
| SCHEMBL20042717 | 0.81 | MEN1 (0.36) | MEN1KMT2AALDH1A1MAP4K4TSHR | |
| SCHEMBL20042678 | 0.75 | DDB1 (0.39) | PDE8BGPR119DDB1CRBNPARP1 | |
| SCHEMBL20042859 | 0.72 | MEN1 (0.35) | MEN1KMT2AALDH1A1GPR119MAP4K4 | |
| SCHEMBL21847945 | 0.72 | MEN1 (0.40) | MEN1KMT2AALDH1A1GPR119MAP4K4 | |
| SCHEMBL27270487 | 0.71 | MEN1 (0.34) | MEN1KMT2AALDH1A1MAP4K4TSHR | |
| SCHEMBL20042838 | 0.69 | PDE10A (0.35) | MEN1KMT2AALDH1A1GPR119MAP4K4 | |
| SCHEMBL31615020 | 0.69 | PDE10A (0.35) | MEN1KMT2AALDH1A1GPR119MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |