Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27270438 | 0.88 | MEN1 (0.37) | MEN1KMT2AMAP4K4SCN4AL3MBTL1 | |
| SCHEMBL20042859 | 0.86 | MEN1 (0.35) | MEN1KMT2AMAP4K4GPR119PTPN1 | |
| SCHEMBL20042723 | 0.84 | PDE8B (0.38) | MEN1KMT2AMAP4K4GPR119SCN4A | |
| SCHEMBL20042717 | 0.84 | MEN1 (0.36) | MEN1KMT2AMAP4K4L3MBTL1ALDH1A1 | |
| SCHEMBL20042908 | 0.84 | MEN1 (0.39) | MEN1KMT2AGPR119PTPN1SCN4A | |
| SCHEMBL31615020 | 0.82 | PDE10A (0.35) | MEN1KMT2AMAP4K4GPR119SCN4A | |
| SCHEMBL20042875 | 0.82 | PDE10A (0.35) | MEN1KMT2AMAP4K4GPR119SCN4A | |
| SCHEMBL31615013 | 0.82 | PDE10A (0.35) | MEN1KMT2AMAP4K4GPR119SCN4A | |
| SCHEMBL20042838 | 0.82 | PDE10A (0.35) | MEN1KMT2AMAP4K4GPR119SCN4A | |
| SCHEMBL31614910 | 0.82 | PDE10A (0.35) | MEN1KMT2AMAP4K4GPR119SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |