Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042800 | 0.82 | CNR1 (0.45) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042806 | 0.82 | CNR1 (0.47) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042779 | 0.82 | GPR55 (0.39) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042764 | 0.81 | CNR1 (0.49) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042660 | 0.81 | CNR1 (0.39) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042691 | 0.80 | PIK3CD (0.38) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042785 | 0.80 | CNR2 (0.36) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042793 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042816 | 0.80 | CNR1 (0.45) | SMN1; SMN2LMNATSHRNR4A1GPR55 | |
| SCHEMBL20042870 | 0.79 | KDM4E (0.35) | SMN1; SMN2LMNATSHRNR4A1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |