Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042806 | 0.99 | CNR1 (0.47) | CNR1GPR55GBA1ALDH1A1TSHR | |
| SCHEMBL20042800 | 0.96 | CNR1 (0.45) | CNR1GPR55GBA1ALDH1A1TSHR | |
| SCHEMBL20042816 | 0.90 | CNR1 (0.45) | CNR1GPR55GBA1ALDH1A1TSHR | |
| SCHEMBL20042706 | 0.89 | ALDH1A1 (0.43) | CNR1GPR55ALDH1A1TSHRLMNA | |
| SCHEMBL20042779 | 0.88 | GPR55 (0.39) | CNR1GPR55GBA1ALDH1A1TSHR | |
| SCHEMBL20042735 | 0.87 | CNR2 (0.41) | CNR1GPR55GBA1ALDH1A1TSHR | |
| SCHEMBL20042660 | 0.86 | CNR1 (0.39) | CNR1GPR55GBA1ALDH1A1TSHR | |
| SCHEMBL20042718 | 0.86 | CNR2 (0.40) | CNR1GPR55GBA1ALDH1A1TSHR | |
| SCHEMBL20042762 | 0.86 | CNR1 (0.40) | CNR1GPR55GBA1ALDH1A1TSHR | |
| SCHEMBL20042793 | 0.85 | SMN1; SMN2 (0.37) | CNR1GPR55GBA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |