SCHEMBL200428

SCHEMBL200428

O=C(O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.88
PARP10 Q53GL7 2/20 0.69
PARP15 Q460N3 1/20 0.69
PKM P14618 1/20 0.67
AKR1C3 P42330 1/20 0.67
TSHR P16473 3/20 0.59
DAO P14920 1/20 0.59
NAPRT Q6XQN6 1/20 0.59
POLB P06746 1/20 0.58
ERCC5 P28715 1/20 0.58
FEN1 P39748 1/20 0.58
TTR P02766 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
LTA4H P09960 1/20 0.57
NR1H4 Q96RI1 1/20 0.57
TP53 P04637 1/20 0.57
NR4A1 P22736 1/20 0.57
NR4A2 P43354 1/20 0.57
NR4A3 Q92570 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1888572 1.00 SRD5A2 (0.88) SRD5A2PARP10PARP15PKMAKR1C3
SCHEMBL6892687 1.00 SRD5A2 (0.88) SRD5A2PARP10PARP15PKMAKR1C3
Ammonia Solution, Strong SCHEMBL18151747 0.98 SRD5A2 (0.84) SRD5A2PARP10PARP15PKMAKR1C3
Hydrochloric Acid SCHEMBL10520761 0.98 SRD5A2 (0.84) SRD5A2PARP10PARP15PKMAKR1C3
Diphenylether SCHEMBL27807374 0.98 SRD5A2 (0.83) SRD5A2PARP10PARP15PKMAKR1C3
Diphenylether SCHEMBL17104399 0.95 SRD5A2 (0.80) SRD5A2PARP10PARP15PKMAKR1C3
Benzoic Acid SCHEMBL3021235 0.95 SRD5A2 (0.80) SRD5A2PARP10PARP15PKMAKR1C3
SCHEMBL8999835 0.94 SRD5A2 (0.78) SRD5A2PARP10PARP15PKMAKR1C3
SCHEMBL7822422 0.94 SRD5A2 (1.00) SRD5A2PARP10PARP15PKMAKR1C3
Diphenylether SCHEMBL1926311 0.93 SRD5A2 (0.76) SRD5A2PARP10PARP15PKMAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1933 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136948-A Cycloastragal derivative with activity of resisting methicillin-resistant staphylococcus aureus and preparation method thereof 山西医科大学 2025-06-13 CN claimed
CN-119874466-A N, N-dimethylamide compound and synthesis method thereof 海南大学 2025-04-25 CN claimed
CN-119859148-A Spiroteine framework compound and preparation method and application thereof 安徽农业大学 2025-04-22 CN claimed
CN-116947863-B (4-Phenoxyphenyl) (pyrrolopyrimidine-5-yl) ketone compound and preparation method and application thereof 中国药科大学 2025-04-11 CN claimed
CN-119569566-A Crystal form of 4-phenoxybenzoic acid and preparation method thereof 合肥菁科生物科技有限公司 2025-03-07 CN claimed
CN-118955316-A Preparation method of roflumilast intermediate 石家庄龙泽制药股份有限公司 2024-11-15 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-115894500-B Compound serving as BTK kinase inhibitor and preparation method and application thereof 中国药科大学 2024-05-28 CN claimed
CN-116947863-A (4-phenoxyphenyl) (pyrrolopyrimidine-5-yl) ketone compound and preparation method and application thereof 中国药科大学 2023-10-27 CN claimed
CN-110511225-B Synthesis method of ibutinib intermediate 杭州中美华东制药有限公司 2023-07-18 CN claimed
US-4721771-A Preparation of aromatic polymers RAYCHEM CORPORATION (US) 1988-01-26 US claimed
US-4603220-A Process for the preparation of aromatic monocarboxylic acids from toluene and substituted toluenes DYNAMIT NOBEL AG (DE) 1986-07-29 US claimed
EP-0178871-A2 Preparation of aromatic polymers RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-23 EP claimed
EP-0070393-B1 PROCESS FOR THE PREPARATION OF AROMATIC MONOCARBOXYLIC ACIDS HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1985-05-29 EP claimed
EP-0069597-B1 PREPARING P-PHENOXY-BENZOYL COMPOUNDS RAYCHEM CORPORATION (a California corporation) (US) 1984-10-10 EP claimed
US-4474990-A Preparing p-phenoxy benzoyl compounds RAYCHEM CORPORATION (US) 1984-10-02 US claimed
EP-0060943-B1 PARAPHENOXYBENZOTRICHLORIDE, ITS PREPARATION AND USE OCCIDENTAL CHEMICAL CORPORATION (US) 1984-06-13 EP claimed
EP-0069597-A1 Preparing p-phenoxy-benzoyl compounds RAYCHEM CORPORATION (a California corporation) (US) 1983-01-12 EP claimed
EP-0060943-A1 Paraphenoxybenzotrichloride, its preparation and use OCCIDENTAL CHEMICAL CORPORATION (US) 1982-09-29 EP claimed
US-4268457-A Process for the preparation of paraphenoxybenzoylchloride HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-05-19 US claimed