SCHEMBL8999835

SCHEMBL8999835

O=C(O)c1ccc(-c2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.78
PARP10 Q53GL7 2/20 0.62
PARP15 Q460N3 1/20 0.62
PKM P14618 1/20 0.60
AKR1C3 P42330 1/20 0.60
HSD17B10 Q99714 1/20 0.58
MCL1 Q07820 2/20 0.55
BCL2L1 Q07817 1/20 0.55
POLB P06746 1/20 0.54
IP6K1 Q92551 1/20 0.54
IP6K3 Q96PC2 1/20 0.54
IP6K2 Q9UHH9 1/20 0.54
CHEK2 O96017 1/20 0.54
EGFR P00533 1/20 0.53
ERCC5 P28715 1/20 0.53
FEN1 P39748 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419154 0.96 SRD5A2 (0.71) SRD5A2PARP10PARP15PKMAKR1C3
SCHEMBL200428 0.94 SRD5A2 (0.88) SRD5A2PARP10PARP15PKMAKR1C3
SCHEMBL31202650 0.94 PARP15 (0.69) SRD5A2PARP10PARP15HSD17B10BCL2L1
SCHEMBL1888572 0.94 SRD5A2 (0.88) SRD5A2PARP10PARP15PKMAKR1C3
SCHEMBL6892687 0.94 SRD5A2 (0.88) SRD5A2PARP10PARP15PKMAKR1C3
SCHEMBL30307442 0.94 PARP15 (0.69) SRD5A2PARP10PARP15HSD17B10BCL2L1
SCHEMBL2748100 0.94 PARP15 (0.69) SRD5A2PARP10PARP15HSD17B10BCL2L1
Biphenyl SCHEMBL20561236 0.92 SRD5A2 (0.71) SRD5A2PARP10PARP15PKMAKR1C3
Hydrochloric Acid SCHEMBL10520761 0.91 SRD5A2 (0.84) SRD5A2PARP10PARP15PKMAKR1C3
Ammonia Solution, Strong SCHEMBL18151747 0.91 SRD5A2 (0.84) SRD5A2PARP10PARP15PKMAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108762-A Active ester resin with phosphorus and self-extinguishing characteristic structure, and preparation method and application thereof 四川东材科技集团股份有限公司 2024-05-31 CN claimed
US-12378224-B2 Heteroaryl compounds and their use as Mer inhibitors DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2025-08-05 US disclosed
CN-118108762-A Active ester resin with phosphorus and self-extinguishing characteristic structure, and preparation method and application thereof 四川东材科技集团股份有限公司 2024-05-31 CN disclosed
US-11358924-B2 Dissociation of a 1,4-bis (4-phenoxybenzoyl)benzene-lewis acid complex in an aqueous solution ARKEMA FRANCE (FR) 2022-06-14 US disclosed
EP-3523292-B1 HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS DONG A SOCIO HOLDINGS CO LTD (KR) 2021-12-15 EP disclosed
US-20210371398-A1 HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS DONG A SOCIO HOLDINGS CO LTD (KR) 2021-12-02 US disclosed
US-20210363088-A1 METHOD FOR MANUFACTURING 1,4-BIS (4-PHENOXYBENZOYL)BENZENE AT AN ELEVATED TEMPERATURE ARKEMA FRANCE (FR) 2021-11-25 US disclosed
US-20210155571-A1 PURIFICATION OF 1,4-BIS (4-PHENOXYBENZOYL)BENZENE BY CENTRIFUGAL FILTRATION ARKEMA FRANCE (FR) 2021-05-27 US disclosed
US-10981852-B2 Ripening of 1,4-bis (4-phenoxybenzoyl)benzene ARKEMA FRANCE (FR) 2021-04-20 US disclosed
US-10913730-B2 Heteroaryl compounds and their use as Mer inhibitors DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2021-02-09 US disclosed
EP-0465048-B1 Carboxylic acid ester compound, liquid crystal compound, liquid crystal composition, liquid crystal element and light modulation method MITSUI PETROCHEMICAL IND (JP) 1996-09-11 EP disclosed
EP-0368006-B1 Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties DOW CHEMICAL CO (US) 1995-04-05 EP disclosed
US-5151489-A Block copolymers for compression molding to form fibers, films and laminates THE DOW CHEMICAL COMPANY (US) 1992-09-29 US disclosed
US-5098985-A Block copolymers for films, fibers, laminates or compression moldings THE DOW CHEMICAL COMPANY (US) 1992-03-24 US disclosed
US-5089568-A Block polymers THE DOW CHEMICAL COMPANY (US) 1992-02-18 US disclosed
EP-0392008-A4 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES 1991-09-04 EP disclosed
US-5030706-A With acrylation reactive end groups THE DOW CHEMICAL COMPANY (US) 1991-07-09 US disclosed
EP-0392008-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-10-17 EP disclosed
EP-0368006-A2 Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties THE DOW CHEMICAL COMPANY (US) 1990-05-16 EP disclosed
WO-1990003995-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10913730-B2 Heteroaryl compounds and their use as Mer inhibitors MERTK, RET, ERBB4 SRD5A2 2211/4885PARP10 2572/4885PARP15 3324/4885
US-12378224-B2 Heteroaryl compounds and their use as Mer inhibitors MERTK, RET, ERBB2 SRD5A2 1974/4885PARP10 3343/4885PARP15 4023/4885
US-20210363088-A1 METHOD FOR MANUFACTURING 1,4-BIS (4-PHENOXYBENZOYL)BENZENE AT AN ELEVATED TEMPERATURE TERT, TLL2, TLL1 SRD5A2 3693/4885PARP10 3121/4885PARP15 2334/4885
US-20210371398-A1 HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS MERTK, RET, ERBB2 SRD5A2 1974/4885PARP10 3343/4885PARP15 4023/4885
US-11358924-B2 Dissociation of a 1,4-bis (4-phenoxybenzoyl)benzene-lewis acid complex in an aqueous solution SSB, PBRM1, TLL2 SRD5A2 3802/4885PARP10 4548/4885PARP15 4184/4885
US-20210155571-A1 PURIFICATION OF 1,4-BIS (4-PHENOXYBENZOYL)BENZENE BY CENTRIFUGAL FILTRATION PBRM1, PSMB4, PSMC1 SRD5A2 4039/4885PARP10 4507/4885PARP15 4100/4885
US-10981852-B2 Ripening of 1,4-bis (4-phenoxybenzoyl)benzene PSMC4, PSMB4, PSMC6 SRD5A2 4444/4885PARP10 3956/4885PARP15 3677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.