Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042845 | 0.84 | MEN1 (0.36) | MEN1KMT2AALDH1A1L3MBTL1SCN5A | |
| SCHEMBL20042891 | 0.83 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1L3MBTL1SCN5A | |
| SCHEMBL16035077 | 0.75 | P2RX7 (0.38) | — | |
| SCHEMBL20042717 | 0.73 | MEN1 (0.36) | MEN1KMT2AALDH1A1L3MBTL1PIK3CD | |
| SCHEMBL20042859 | 0.72 | MEN1 (0.35) | MEN1KMT2AALDH1A1L3MBTL1SCN5A | |
| SCHEMBL27270438 | 0.72 | MEN1 (0.37) | MEN1KMT2AALDH1A1L3MBTL1SCN5A | |
| SCHEMBL20042838 | 0.69 | PDE10A (0.35) | MEN1KMT2AALDH1A1L3MBTL1SCN5A | |
| SCHEMBL31615020 | 0.69 | PDE10A (0.35) | MEN1KMT2AALDH1A1L3MBTL1SCN5A | |
| SCHEMBL31614910 | 0.69 | PDE10A (0.35) | MEN1KMT2AALDH1A1L3MBTL1SCN5A | |
| SCHEMBL31615013 | 0.69 | PDE10A (0.35) | MEN1KMT2AALDH1A1L3MBTL1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |