Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042874 | 0.75 | NPY5R (0.36) | NPY5RCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL20042736 | 0.75 | NPY5R (0.36) | NPY5RCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL20042907 | 0.73 | NPY5R (0.37) | NPY5RCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL31614818 | 0.69 | NPY5R (0.39) | NPY5RCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL20042683 | 0.69 | NPY5R (0.39) | NPY5RCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL31614807 | 0.68 | MAP2K7 (0.32) | NPY5RGUSBSMN1; SMN2 | |
| SCHEMBL31614998 | 0.68 | MAP2K7 (0.32) | NPY5RGUSBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31614730 | 0.68 | MEN1 (0.39) | NPY5RCHRM3PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL31405518 | 0.68 | MEN1 (0.39) | NPY5RCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL20042895 | 0.63 | NPY5R (0.35) | NPY5RCHRM3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |