Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042874 | 1.00 | NPY5R (0.36) | NPY5RGUSBCHRM3PDE4APDE4B | |
| SCHEMBL31614807 | 0.91 | MAP2K7 (0.32) | NPY5RGUSBSMN1; SMN2PDK2PDK4 | |
| SCHEMBL31614998 | 0.91 | MAP2K7 (0.32) | NPY5RGUSBSMN1; SMN2PDK2PDK4 | |
| SCHEMBL20042895 | 0.81 | NPY5R (0.35) | NPY5RGUSBCHRM3PDE4APDE4B | |
| SCHEMBL20042731 | 0.81 | CHRM3 (0.51) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042984 | 0.81 | NPY5R (0.35) | NPY5RHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL20042890 | 0.75 | NPY5R (0.36) | NPY5RGUSBCHRM3PDE4APDE4B | |
| SCHEMBL20042907 | 0.73 | NPY5R (0.37) | NPY5RGUSBCHRM3PDE4APDE4B | |
| SCHEMBL31614818 | 0.69 | NPY5R (0.39) | NPY5RCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL20042683 | 0.69 | NPY5R (0.39) | NPY5RCHRM3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |