Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20043042 | 0.85 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL20043057 | 0.79 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL9464507 | 0.75 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E | |
| SCHEMBL16350574 | 0.74 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E | |
| SCHEMBL362773 | 0.74 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E | |
| SCHEMBL6160104 | 0.72 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E | |
| SCHEMBL3305715 | 0.72 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E | |
| SCHEMBL5485685 | 0.72 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E | |
| SCHEMBL6160109 | 0.72 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL4886939 | 0.70 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180100036-A1 | CLICK NUCLEIC ACID POLYMERS AND METHODS OF USE | UNIV COLORADO REGENTS (US) | 2018-04-12 | — | — | US | disclosed |