Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N,N-Diallyl-2-Chloroacetamide SCHEMBL4886939 | 0.82 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL53540 | 0.82 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| SCHEMBL362773 | 0.81 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| SCHEMBL16350574 | 0.81 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL8953543 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL20819425 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| SCHEMBL3305715 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| SCHEMBL6160104 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| SCHEMBL6160109 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 | |
| SCHEMBL8068413 | 0.77 | ALDH1A1 (0.91) | ALDH1A1SMN1; SMN2POLBMAPTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293553-A1 | Diphenylurea Derivatives Useful As Potassium Channel Activators | NEUROSEARCH A/S (DK) | 2007-12-20 | — | — | US | claimed |
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | claimed |
| WO-1998033776-A1 | COMBINATORIAL LIBRARIES OF HYDANTOIN AND THIOHYDANTOIN DERIVATIVES, METHODS OF MAKING THE LIBRARIES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| US-4962202-A | PENICILLIN INTERMEDIATES | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-10-09 | — | — | US | claimed |
| US-20070293553-A1 | Diphenylurea Derivatives Useful As Potassium Channel Activators | NEUROSEARCH A/S (DK) | 2007-12-20 | — | — | US | disclosed |
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293553-A1 | Diphenylurea Derivatives Useful As Potassium Channel Activators | KCNJ2, KCNH2, KCNH3 | ALDH1A1 418/4885SMN1; SMN2 2422/4885POLB 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.