Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20043061 | 0.83 | EGFR (0.53) | ADORA2AEGFRADCY5PI4KAPI4K2B | |
| SCHEMBL20043068 | 0.79 | ADORA2A (0.58) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL20043071 | 0.74 | EGFR (0.35) | ADORA2AEGFRADCY5LMNAHPGD | |
| SCHEMBL20043063 | 0.74 | ALDH1A1 (0.56) | ADORA2AEGFRPI4KAPI4K2BPI4K2A | |
| SCHEMBL20043044 | 0.69 | KIF11 (0.38) | — | |
| SCHEMBL20043066 | 0.67 | ADORA2A (0.52) | ADORA2AEGFRADCY5PI4KAPI4K2B | |
| SCHEMBL13417625 | 0.67 | ADCY5 (0.57) | ADORA2AEGFRADCY5PI4KAPI4K2B | |
| SCHEMBL24322117 | 0.66 | ADORA2A (0.60) | ADORA2AADCY5ADORA1ADORA2BLMNA | |
| SCHEMBL983769 | 0.66 | ADORA2A (0.68) | ADORA2AEGFRADCY5PI4KAPI4K2B | |
| Methylglyoxal SCHEMBL6013428 | 0.66 | ADORA2A (0.67) | ADORA2AEGFRADCY5PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180100036-A1 | CLICK NUCLEIC ACID POLYMERS AND METHODS OF USE | UNIV COLORADO REGENTS (US) | 2018-04-12 | — | — | US | disclosed |