Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 4/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.89 |
| ▸ | IGF1R | P08069 | 1/20 | 0.89 |
| ▸ | BACE1 | P56817 | 5/20 | 0.58 |
| ▸ | BCL2 | P10415 | 4/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.58 |
| ▸ | SNCA | P37840 | 4/20 | 0.58 |
| ▸ | PGD | P52209 | 4/20 | 0.58 |
| ▸ | MET | P08581 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.58 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17972588 | 1.00 | HSP90AB1 (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL17220841 | 1.00 | HSP90AB1 (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL17220840 | 1.00 | HSP90AB1 (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL6765008 | 1.00 | HSP90AB1 (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL24984288 | 0.94 | DYRK1A (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL30987004 | 0.94 | DYRK1A (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL30141006 | 0.94 | DYRK1A (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL24983851 | 0.94 | DYRK1A (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL21381204 | 0.88 | HSP90AB1 (0.78) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL19319148 | 0.87 | HSP90AB1 (0.77) | HSP90AB1DYRK1AIGF1RBACE1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308624-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2018-04-12 | — | — | US | disclosed |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308624-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | PNP, PPA1, CDS2 | HSP90AB1 4603/4885DYRK1A 372/4885IGF1R 1063/4885 |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | HSP90AB1 4603/4885DYRK1A 372/4885IGF1R 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.