Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 4/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.89 |
| ▸ | IGF1R | P08069 | 1/20 | 0.89 |
| ▸ | BACE1 | P56817 | 5/20 | 0.58 |
| ▸ | BCL2 | P10415 | 4/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.58 |
| ▸ | SNCA | P37840 | 4/20 | 0.58 |
| ▸ | PGD | P52209 | 4/20 | 0.58 |
| ▸ | MET | P08581 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.58 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20043083 | 1.00 | HSP90AB1 (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL17972588 | 1.00 | HSP90AB1 (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL17220841 | 1.00 | HSP90AB1 (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL17220840 | 1.00 | HSP90AB1 (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL24984288 | 0.94 | DYRK1A (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL30987004 | 0.94 | DYRK1A (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL30141006 | 0.94 | DYRK1A (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL24983851 | 0.94 | DYRK1A (1.00) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL21381204 | 0.88 | HSP90AB1 (0.78) | HSP90AB1DYRK1AIGF1RBACE1BCL2 | |
| SCHEMBL19319148 | 0.87 | HSP90AB1 (0.77) | HSP90AB1DYRK1AIGF1RBACE1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952358-B2 | Flavan-3-ol analogs and anti-inflammatory activity | HONG KONG BAPTIST UNIVERSITY (CN) | 2024-04-09 | — | — | US | disclosed |
| US-20230159482-A1 | FLAVAN-3-OL ANALOGS AND ANTI-INFLAMMATORY ACTIVITY | HONG KONG BAPTIST UNIVERSITY (CN) | 2023-05-25 | — | — | US | disclosed |
| CN-111406755-A | Camellia nitidissima theaflavin medicament for resisting novel coronavirus and preparation method and application thereof | 韶关学院 | 2020-07-14 | — | — | CN | disclosed |
| CN-111406755-A | Camellia nitidissima theaflavin medicament for resisting novel coronavirus and preparation method and application thereof | 韶关学院 | 2020-07-14 | — | — | CN | disclosed |
| US-10308624-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2018-04-12 | — | — | US | disclosed |
| US-9840487-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170217919-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2017-08-03 | — | — | US | disclosed |
| US-9624190-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160221982-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
| US-9309217-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150315168-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-05 | — | — | US | disclosed |
| US-6713506-B2 | INHIBITING PROTEASOMAL CHYMOTRYPSIN-LIKE ACTIVITY | UNIVERSITY OF SOUTH FLORIDA | 2004-03-30 | — | — | US | disclosed |
| US-20020151582-A1 | Tea polyphenol esters and analogs thereof for cancer prevention and treatment | SOUTH FLORIDA, UNIVERSITY OF | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217919-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | HSP90AB1 4603/4885DYRK1A 372/4885IGF1R 1063/4885 |
| US-11952358-B2 | Flavan-3-ol analogs and anti-inflammatory activity | IL1A, IL6, IL1B | HSP90AB1 794/4885DYRK1A 4754/4885IGF1R 1285/4885 |
| US-20160221982-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | HSP90AB1 4603/4885DYRK1A 372/4885IGF1R 1063/4885 |
| US-10308624-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | PNP, PPA1, CDS2 | HSP90AB1 4603/4885DYRK1A 372/4885IGF1R 1063/4885 |
| US-20150315168-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | HSP90AB1 4603/4885DYRK1A 372/4885IGF1R 1063/4885 |
| US-20230159482-A1 | FLAVAN-3-OL ANALOGS AND ANTI-INFLAMMATORY ACTIVITY | IL1A, IL6, IL1B | HSP90AB1 794/4885DYRK1A 4754/4885IGF1R 1285/4885 |
| US-20020151582-A1 | Tea polyphenol esters and analogs thereof for cancer prevention and treatment | GCG, CTSG, CTRL | HSP90AB1 506/4885DYRK1A 4828/4885IGF1R 4632/4885 |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | HSP90AB1 4603/4885DYRK1A 372/4885IGF1R 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.