Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 10/20 | 1.00 |
| ▸ | IGF1R | P08069 | 1/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.89 |
| ▸ | BACE1 | P56817 | 5/20 | 0.66 |
| ▸ | BCL2 | P10415 | 4/20 | 0.66 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.66 |
| ▸ | SNCA | P37840 | 4/20 | 0.66 |
| ▸ | PGD | P52209 | 4/20 | 0.66 |
| ▸ | MET | P08581 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | RECQL | P46063 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.66 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983851 | 1.00 | DYRK1A (1.00) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL24984288 | 1.00 | DYRK1A (1.00) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL30987004 | 1.00 | DYRK1A (1.00) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL17972588 | 0.94 | HSP90AB1 (1.00) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL17220840 | 0.94 | HSP90AB1 (1.00) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL17220841 | 0.94 | HSP90AB1 (1.00) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL20043083 | 0.94 | HSP90AB1 (1.00) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL6765008 | 0.94 | HSP90AB1 (1.00) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL18255324 | 0.89 | DYRK1A (0.79) | DYRK1AIGF1RHSP90AB1BACE1BCL2 | |
| SCHEMBL21381204 | 0.87 | HSP90AB1 (0.78) | DYRK1AIGF1RHSP90AB1BACE1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288020-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES INC. (US) | 2023-01-19 | — | — | WO | disclosed |