Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.39 |
| ▸ | ITGAV | P06756 | 10/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3019725 | 0.90 | MIF (0.47) | MIFITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL3019728 | 0.90 | MIF (0.47) | MIFITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL19449956 | 0.90 | MIF (0.47) | MIFITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL3032267 | 0.80 | CA12 (0.40) | ITGB3ITGAVITGA2BNPC1RAB9A | |
| SCHEMBL3032266 | 0.80 | CA12 (0.40) | ITGB3ITGAVITGA2BNPC1RAB9A | |
| SCHEMBL13014961 | 0.78 | ITGB3 (0.57) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL3023901 | 0.77 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL3023900 | 0.77 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL3024513 | 0.76 | P2RX3 (0.40) | NPC1RAB9APKMMAOAMAOB | |
| SCHEMBL3024515 | 0.76 | P2RX3 (0.40) | NPC1RAB9APKMMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067946-A1 | METHODS OF TREATING PATIENTS WITH A RETINOIC ACID RECEPTOR-ALPHA AGONIST AND AN ANTI-CD38 ANTIBODY | SYROS PHARMACEUTICALS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |