Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324850 | 0.95 | SMN1; SMN2 (0.55) | SMN1; SMN2ALOX5LTA4HHSD17B10ALDH1A1 | |
| SCHEMBL1140947 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2ALOX5LTA4HRORCHSD17B10 | |
| SCHEMBL550428 | 0.90 | ALOX5 (0.60) | SMN1; SMN2ALOX5LTA4HHSD17B10ALDH1A1 | |
| SCHEMBL801363 | 0.90 | ALOX5 (0.50) | SMN1; SMN2ALOX5LTA4HHSD17B10ALDH1A1 | |
| SCHEMBL5176893 | 0.90 | BCHE (0.57) | SMN1; SMN2ALOX5LTA4HHSD17B10ALDH1A1 | |
| SCHEMBL4321470 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2ALOX5LTA4HHSD17B10ALDH1A1 | |
| SCHEMBL9829350 | 0.87 | ALOX5 (0.50) | SMN1; SMN2ALOX5LTA4HHSD17B10ALDH1A1 | |
| SCHEMBL1713228 | 0.87 | ALOX5 (0.63) | SMN1; SMN2ALOX5LTA4HHSD17B10ALDH1A1 | |
| SCHEMBL4847536 | 0.87 | RORC (0.50) | SMN1; SMN2ALOX5LTA4HRORCHSD17B10 | |
| SCHEMBL9730917 | 0.86 | ALOX5 (0.60) | SMN1; SMN2ALOX5LTA4HALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099956-A1 | Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating | MITHRIDION, INC. | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099956-A1 | Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating | CHRM3, CHRM4, CHRM5 | SMN1; SMN2 1001/4885ALOX5 246/4885LTA4H 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.