Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.64 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.64 |
| ▸ | HRH1 | P35367 | 1/20 | 0.64 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.64 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.64 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.64 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910958 | 0.90 | CHRM2 (0.68) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| SCHEMBL2933098 | 0.86 | CHRM2 (0.66) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| SCHEMBL12441787 | 0.86 | CHRM2 (0.66) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| SCHEMBL10516359 | 0.83 | CHRM2 (0.64) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| SCHEMBL10392382 | 0.83 | CHRM2 (0.64) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| SCHEMBL7442966 | 0.83 | CHRM2 (0.63) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| Tridihexethyl SCHEMBL2296006 | 0.83 | CHRM2 (1.00) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| Tridihexethyl SCHEMBL94230 | 0.83 | CHRM2 (1.00) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| SCHEMBL9782807 | 0.83 | CHRM2 (0.62) | CHRM2CHRM1CYP2D6KCNH2CHRM3 | |
| Tridihexethyl SCHEMBL100471 | 0.82 | CHRM2 (0.97) | CHRM2CHRM1CYP2D6KCNH2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414771-B2 | Compounds useful for inhibiting metastasis from cancer and methods using same | DREXEL UNIVERSITY (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180099972-A1 | Compounds Useful for Inhibiting Metastasis from Cancer and Methods Using Same | UNIV DREXEL (US) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099972-A1 | Compounds Useful for Inhibiting Metastasis from Cancer and Methods Using Same | CX3CR1, CCL2, CCR5 | CHRM2 273/4885CHRM1 480/4885CYP2D6 1623/4885 |
| US-10414771-B2 | Compounds useful for inhibiting metastasis from cancer and methods using same | CX3CR1, CCL2, CCR5 | CHRM2 273/4885CHRM1 480/4885CYP2D6 1623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.