Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002576 | 1.00 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL1997295 | 1.00 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL2004853 | 0.99 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL2007424 | 0.99 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL2004499 | 0.99 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| Oleyl Alcohol SCHEMBL4258641 | 0.94 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| Oleyl Alcohol SCHEMBL4263584 | 0.94 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL27704894 | 0.92 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL3806764 | 0.86 | TSHR (0.53) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL8356570 | 0.86 | TSHR (0.53) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150157588-A1 | Pharmaceutical Composition Comprising Amino-Phenyl-Acetic Acid Octadec-(Z)-9-enyl Ester and Use Thereof for Treating Tumors | YEDA RES & DEV (IL) | 2015-06-11 | — | — | US | claimed |
| US-7964751-B2 | Psoriasis, alopecia, contact dermatitis, atopic dermatitis, allergies, vitiligo or inflammatory skin disorders; esterification reaction of oleyl alcohol and a stereoisomer of phenylglycine chloride hydrochloride in a polar aprotic solvent | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2011-06-21 | — | — | US | claimed |
| EP-2117301-A1 | USE OF LONG-CHAIN ALCOHOL DERIVATIVES FOR THE TREATMENT OF ALOPECIA AREATA | Yeda Research And Development Co. Ltd. At The Weizmann Institute of Science (IL) | 2009-11-18 | — | — | EP | claimed |
| EP-2114155-A1 | ENANTIOMERS OF AMINO-PHENYL-ACETIC ACID OCTADEC- 9- (Z) ENYL ESTER, THEIR SALTS AND THEIR USES | Yeda Research And Development Co. Ltd. At The Weizmann Institute of Science (IL) | 2009-11-11 | — | — | EP | claimed |
| US-20080221209-A1 | Psoriasis, alopecia, contact dermatitis, atopic dermatitis, allergies, vitiligo or inflammatory skin disorders; esterification reaction of oleyl alcohol and a stereoisomer of phenylglycine chloride hydrochloride in a polar aprotic solvent | YEDA RESEARCH AND DEVELOPMENT CO. (IL) | 2008-09-11 | — | — | US | claimed |
| WO-2008106091-A1 | USE OF LONG-CHAIN ALCOHOL DERIVATIVES FOR THE TREATMENT OF ALOPECIA AREATA | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-09-04 | — | — | WO | claimed |
| WO-2008106092-A1 | ENANTIOMERS OF AMINO-PHENYL-ACETIC ACID OCTADEC- 9- (Z) ENYL ESTER, THEIR SALTS AND THEIR USES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-09-04 | — | — | WO | claimed |
| US-20150157588-A1 | Pharmaceutical Composition Comprising Amino-Phenyl-Acetic Acid Octadec-(Z)-9-enyl Ester and Use Thereof for Treating Tumors | YEDA RES & DEV (IL) | 2015-06-11 | — | — | US | disclosed |
| US-20150157588-A1 | Pharmaceutical Composition Comprising Amino-Phenyl-Acetic Acid Octadec-(Z)-9-enyl Ester and Use Thereof for Treating Tumors | YEDA RES & DEV (IL) | 2015-06-11 | — | — | US | disclosed |
| US-20150157588-A1 | Pharmaceutical Composition Comprising Amino-Phenyl-Acetic Acid Octadec-(Z)-9-enyl Ester and Use Thereof for Treating Tumors | YEDA RES & DEV (IL) | 2015-06-11 | — | — | US | disclosed |
| EP-2870135-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AMINO-PHENYL- ACETIC ACID OCTADEC-(Z)-9-ENYL ESTER AND USE THEREOF FOR TREATING TUMORS | Yeda Research and Development Co. Ltd. (IL) | 2015-05-13 | — | — | EP | disclosed |
| WO-2014006625-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AMINO-PHENYL- ACETIC ACID OCTADEC-(Z)-9-ENYL ESTER AND USE THEREOF FOR TREATING TUMORS | YEDA RESEARCH AND DEVELOPMENT CO. LTD (IL) | 2014-01-09 | — | — | WO | disclosed |
| WO-2014006625-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AMINO-PHENYL- ACETIC ACID OCTADEC-(Z)-9-ENYL ESTER AND USE THEREOF FOR TREATING TUMORS | YEDA RESEARCH AND DEVELOPMENT CO. LTD (IL) | 2014-01-09 | — | — | WO | disclosed |
| US-7964751-B2 | Psoriasis, alopecia, contact dermatitis, atopic dermatitis, allergies, vitiligo or inflammatory skin disorders; esterification reaction of oleyl alcohol and a stereoisomer of phenylglycine chloride hydrochloride in a polar aprotic solvent | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2011-06-21 | — | — | US | disclosed |
| EP-2114155-A1 | ENANTIOMERS OF AMINO-PHENYL-ACETIC ACID OCTADEC- 9- (Z) ENYL ESTER, THEIR SALTS AND THEIR USES | Yeda Research And Development Co. Ltd. At The Weizmann Institute of Science (IL) | 2009-11-11 | — | — | EP | disclosed |
| US-20080221209-A1 | Psoriasis, alopecia, contact dermatitis, atopic dermatitis, allergies, vitiligo or inflammatory skin disorders; esterification reaction of oleyl alcohol and a stereoisomer of phenylglycine chloride hydrochloride in a polar aprotic solvent | YEDA RESEARCH AND DEVELOPMENT CO. (IL) | 2008-09-11 | — | — | US | disclosed |
| US-20080221209-A1 | Psoriasis, alopecia, contact dermatitis, atopic dermatitis, allergies, vitiligo or inflammatory skin disorders; esterification reaction of oleyl alcohol and a stereoisomer of phenylglycine chloride hydrochloride in a polar aprotic solvent | YEDA RESEARCH AND DEVELOPMENT CO. (IL) | 2008-09-11 | — | — | US | disclosed |
| US-20080221209-A1 | Psoriasis, alopecia, contact dermatitis, atopic dermatitis, allergies, vitiligo or inflammatory skin disorders; esterification reaction of oleyl alcohol and a stereoisomer of phenylglycine chloride hydrochloride in a polar aprotic solvent | YEDA RESEARCH AND DEVELOPMENT CO. (IL) | 2008-09-11 | — | — | US | disclosed |
| WO-2008106092-A1 | ENANTIOMERS OF AMINO-PHENYL-ACETIC ACID OCTADEC- 9- (Z) ENYL ESTER, THEIR SALTS AND THEIR USES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008106092-A1 | ENANTIOMERS OF AMINO-PHENYL-ACETIC ACID OCTADEC- 9- (Z) ENYL ESTER, THEIR SALTS AND THEIR USES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221209-A1 | Psoriasis, alopecia, contact dermatitis, atopic dermatitis, allergies, vitiligo or inflammatory skin disorders; esterification reaction of oleyl alcohol and a stereoisomer of phenylglycine chloride hydrochloride in a polar aprotic solvent | HLA-DRB1, HLA-C, HLA-A | NPC1 3722/4885RAB9A 3158/4885SMN1; SMN2 4843/4885 |
| US-20150157588-A1 | Pharmaceutical Composition Comprising Amino-Phenyl-Acetic Acid Octadec-(Z)-9-enyl Ester and Use Thereof for Treating Tumors | SLC10A1, CA9, AADAT | NPC1 1868/4885RAB9A 468/4885SMN1; SMN2 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.