Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484517 | 0.80 | — | — | |
| SCHEMBL21669921 | 0.79 | GRIN2D (0.36) | CHRM2LMNACYP2C9GABRPGABRD | |
| SCHEMBL16582698 | 0.76 | LMNA (0.35) | LMNACYP2C9GABRPGABRDGABRA1 | |
| SCHEMBL13076899 | 0.74 | LMNA (0.34) | LMNACYP2C9GABRPGABRDGABRA1 | |
| SCHEMBL20354966 | 0.73 | CHRNA7 (0.33) | NEK2 | |
| SCHEMBL9965123 | 0.72 | LMNA (0.34) | LMNACYP2C9GABRPGABRDGABRA1 | |
| SCHEMBL21739432 | 0.72 | NEK2 (0.36) | CHRM2NEK2LMNA | |
| SCHEMBL15371665 | 0.72 | CHRM2 (0.41) | CHRM2CHRM3NEK2 | |
| SCHEMBL5254577 | 0.71 | GABRP (0.32) | NEK2LMNACYP2C9GABRPGABRD | |
| Hydrochloric Acid SCHEMBL5766880 | 0.69 | GABRP (0.32) | NEK2LMNACYP2C9GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067615-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |