Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328882 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL23038402 | 0.81 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL908777 | 0.81 | MAPK1 (0.50) | ALDH1A1MAPK1LMNAHSD17B10 | |
| SCHEMBL23047930 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL23048071 | 0.79 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL23038547 | 0.78 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL17653864 | 0.78 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL20181863 | 0.77 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL23376773 | 0.77 | GLA (0.45) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL15157003 | 0.75 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067615-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |