Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 19/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 16/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20047176 | 0.92 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20047020 | 0.89 | MEN1 (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL20047024 | 0.87 | CHRM5 (0.41) | — | |
| SCHEMBL20047032 | 0.83 | KMT2A (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL20047022 | 0.82 | MEN1 (0.43) | CYP3A4CYP2C19 | |
| SCHEMBL20047023 | 0.82 | AKR1C3 (0.49) | CYP11B1CYP11B2CYP3A4CYP2C19 | |
| SCHEMBL20047031 | 0.81 | AKR1C3 (0.48) | CYP11B1CYP11B2 | |
| SCHEMBL20047027 | 0.80 | PKM (0.51) | CYP3A4CYP2C19 | |
| SCHEMBL20047177 | 0.80 | L3MBTL1 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL20047021 | 0.79 | AKR1C3 (0.45) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017223514-A9 | LXR INVERSE AGONISTS FOR TREATMENT OF CANCER | SAINT LOUIS UNIVERSITY (US) | 2018-04-12 | — | — | WO | disclosed |