Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 9/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CYBB | P04839 | 1/20 | 0.35 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029526 | 1.00 | MAPK14 (0.45) | MAPK14DPP4NCF1CHRNA7CYBB | |
| SCHEMBL22994946 | 0.91 | MAPK14 (0.41) | MAPK14DPP4NCF1CHRNA7CYBB | |
| SCHEMBL18850692 | 0.85 | CHRNA7 (0.38) | MAPK14DPP4NCF1CHRNA7DRD2 | |
| SCHEMBL15281111 | 0.85 | CHRNA7 (0.38) | MAPK14DPP4NCF1CHRNA7DRD2 | |
| SCHEMBL15223677 | 0.85 | CHRNA7 (0.38) | MAPK14DPP4NCF1CHRNA7DRD2 | |
| SCHEMBL17586038 | 0.85 | CHRNA7 (0.38) | MAPK14DPP4NCF1CHRNA7DRD2 | |
| SCHEMBL15976248 | 0.84 | GBA1 (0.39) | DPP4NCF1CHRNA7CYBBNOX5 | |
| SCHEMBL22906473 | 0.81 | DPP4 (0.35) | MAPK14DPP4NCF1CHRNA7CYBB | |
| SCHEMBL18850696 | 0.81 | DPP4 (0.35) | MAPK14DPP4NCF1CHRNA7CYBB | |
| SCHEMBL17740224 | 0.80 | NCF1 (0.43) | MAPK14NCF1CYBBNOX5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127190-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2018067615-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |