Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148729 | 0.78 | — | — | |
| SCHEMBL31275518 | 0.73 | SIGMAR1 (0.44) | TSHR | |
| SCHEMBL22561533 | 0.73 | TSHR (0.35) | TSHRMAOBMAOA | |
| SCHEMBL17136154 | 0.73 | TSHR (0.35) | TSHRMAOBMAOA | |
| SCHEMBL15700605 | 0.73 | TSHR (0.35) | TSHRMAOBMAOA | |
| SCHEMBL7519293 | 0.73 | SIGMAR1 (0.44) | TSHR | |
| SCHEMBL31089138 | 0.70 | — | — | |
| SCHEMBL21670221 | 0.70 | MAOB (0.31) | TSHRMAOB | |
| SCHEMBL24443744 | 0.69 | — | — | |
| SCHEMBL31275530 | 0.68 | BCHE (0.36) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067615-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |