Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | EBP | Q15125 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275518 | 1.00 | SIGMAR1 (0.44) | SIGMAR1EBPKDM4EHTTCYP2A13 | |
| SCHEMBL17148729 | 0.78 | — | — | |
| SCHEMBL23638497 | 0.77 | SIGMAR1 (0.44) | SIGMAR1EBPKDM4EHTTCYP2A13 | |
| SCHEMBL5805370 | 0.77 | SIGMAR1 (0.44) | SIGMAR1EBPKDM4EHTTCYP2A13 | |
| SCHEMBL23633009 | 0.77 | SIGMAR1 (0.44) | SIGMAR1EBPKDM4EHTTCYP2A13 | |
| SCHEMBL24951989 | 0.77 | SIGMAR1 (0.44) | SIGMAR1EBPKDM4EHTTCYP2A13 | |
| SCHEMBL26817726 | 0.75 | PDK1 (0.41) | PDK1 | |
| SCHEMBL6133223 | 0.74 | SIGMAR1 (0.41) | SIGMAR1EBPKDM4EHTTCYP2A13 | |
| SCHEMBL17136154 | 0.73 | TSHR (0.35) | SIGMAR1KDM4EHTTALDH1A1TSHR | |
| SCHEMBL22561533 | 0.73 | TSHR (0.35) | SIGMAR1KDM4EHTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794009-B1 | BISARYLSULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2017-08-30 | — | — | EP | claimed |
| US-20250257076-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS cGAS INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-14 | — | — | US | disclosed |
| US-20020111273-A1 | Dihydrobenzene pesticides | SZCZEPANSKI HENRY (CH) | 2002-08-15 | — | — | US | disclosed |
| EP-0907634-B1 | PESTICIDES | BAYER AG (DE) | 2002-01-30 | — | — | EP | disclosed |
| EP-0912499-B1 | PESTICIDES | BAYER AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6316389-B1 | PEST CONTROL, IN PARTICULAR AS FUNGICIDES, ACARICIDES AND INSECTICIDES IN CROP PROTECTION. | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6288071-B1 | FUNGICIDES, INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| EP-0912499-A1 | PESTICIDES | Novartis AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| EP-0907634-A1 | PESTICIDES | Novartis AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049672-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997047592-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257076-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS cGAS INHIBITORS | CGAS, SSB, FPGS | SIGMAR1 4506/4885EBP 3496/4885KDM4E 3122/4885 |
| US-20020111273-A1 | Dihydrobenzene pesticides | CYP8B1, CBR1, DHCR24 | SIGMAR1 396/4885EBP 174/4885KDM4E 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.