Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146048 | 1.00 | ALDH1A1 (0.52) | ALDH1A1RECQLPOLBGAAKDM4E | |
| SCHEMBL6929250 | 0.85 | POLB (0.59) | ALDH1A1RECQLPOLBGAAKDM4E | |
| SCHEMBL1745361 | 0.80 | ALDH1A1 (0.66) | ALDH1A1RECQLPOLBGAAKDM4E | |
| SCHEMBL12374731 | 0.79 | ALDH1A1 (0.50) | ALDH1A1RECQLPOLBGAAKDM4E | |
| SCHEMBL17392944 | 0.79 | POLB (0.50) | ALDH1A1RECQLPOLBGAAKDM4E | |
| SCHEMBL6930770 | 0.78 | LMNA (0.70) | ALDH1A1RECQLPOLBGAAKDM4E | |
| SCHEMBL14083741 | 0.77 | ALDH1A1 (0.43) | ALDH1A1RECQLKDM4EHSD17B10GLA | |
| SCHEMBL4011716 | 0.77 | — | — | |
| SCHEMBL19886703 | 0.77 | — | — | |
| SCHEMBL23085722 | 0.76 | ALDH1A1 (0.47) | ALDH1A1RECQLPOLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067615-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |