Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | STAT5B | P51692 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23615871 | 0.72 | KDM4E (0.39) | KDM4ELMNAALDH1A1HPGDSTAT5B | |
| SCHEMBL22096027 | 0.68 | STAT5B (0.66) | KDM4ELMNAALDH1A1HPGDSTAT5B | |
| SCHEMBL14582767 | 0.65 | NPSR1 (0.59) | KDM4ELMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL18990911 | 0.58 | NPSR1 (0.48) | KDM4ELMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL9296458 | 0.58 | NPSR1 (0.48) | KDM4ELMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL23925907 | 0.58 | NPSR1 (0.48) | KDM4ELMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL4115514 | 0.58 | KDM4E (0.49) | KDM4ELMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL11631433 | 0.57 | KDM4E (0.41) | KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL10686855 | 0.54 | — | — | |
| SCHEMBL6440860 | 0.54 | NPSR1 (0.59) | KDM4ELMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018065536-A1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | FREIE UNIVERSITÄT BERLIN (DE) | 2018-04-12 | — | — | WO | disclosed |