Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440864 | 0.91 | SMN1; SMN2 (0.56) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 | |
| SCHEMBL7229858 | 0.89 | SMN1; SMN2 (0.50) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 | |
| SCHEMBL1412516 | 0.86 | SMN1; SMN2 (0.51) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 | |
| SCHEMBL31436306 | 0.84 | SMN1; SMN2 (0.50) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 | |
| SCHEMBL17627087 | 0.84 | SMN1; SMN2 (0.50) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 | |
| SCHEMBL8951086 | 0.75 | NPSR1 (1.00) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 | |
| SCHEMBL1256960 | 0.73 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL5761874 | 0.70 | NPSR1 (0.48) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 | |
| SCHEMBL16453474 | 0.70 | KDM4C (0.53) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 | |
| SCHEMBL19763311 | 0.70 | KDM4C (0.48) | NPSR1SMN1; SMN2KDM4CKDM4ESTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301284-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-05-28 | — | — | US | disclosed |
| EP-1539717-A2 | MICROBIOCIDAL (E.G FUNGICIDAL) 1,2,3-TRIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018438-A2 | MICROBIOCIDAL (E.G. FUNGICIDAL) 1,2,3-TRIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301284-B2 | Therapeutic inhibitory compounds | KLKB1, SERPINB1, SERPINE1 | NPSR1 1946/4885SMN1; SMN2 4577/4885KDM4C 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.