Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 1.00 |
| ▸ | PGR | P06401 | 15/20 | 1.00 |
| ▸ | AR | P10275 | 12/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20048212 | 1.00 | NR3C1 (1.00) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL30324808 | 1.00 | NR3C1 (1.00) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL20048415 | 0.93 | NR3C1 (0.87) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL20048418 | 0.93 | NR3C1 (0.87) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL19042673 | 0.91 | NR3C1 (1.00) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL23653772 | 0.90 | NR3C1 (0.88) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL20048092 | 0.90 | NR3C1 (0.88) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL20048417 | 0.90 | NR3C1 (0.81) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL19042724 | 0.89 | NR3C1 (0.83) | NR3C1PGRARCYP3A4 | |
| SCHEMBL21143406 | 0.88 | NR3C1 (1.00) | NR3C1PGRARCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018068021-A1 | INHIBITORS OF GLUCOCORTICOID RECEPTOR | ORIC PHARMACEUTICALS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |