SCHEMBL2004850

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13122661	0.89	MEN1 (0.49)	SGMS2MAPTMAPK1TDP1L3MBTL1
	SCHEMBL13122181	0.87	L3MBTL1 (0.47)	SGMS2MAPTMAPK1TDP1L3MBTL1
	SCHEMBL13122037	0.84	SGMS2 (0.42)	SGMS2MAPTMAPK1TDP1L3MBTL1
	SCHEMBL21266902	0.82	SGMS2 (0.55)	SGMS2MAPTMAPK1TDP1L3MBTL1
	SCHEMBL13190080	0.79	CDK8 (0.49)	SGMS2MAPTMAPK1TDP1L3MBTL1
	SCHEMBL3778607	0.78	L3MBTL1 (0.47)	SGMS2MAPTMAPK1TDP1L3MBTL1
	SCHEMBL26811483	0.78	SGMS2 (0.51)	SGMS2MAPTMAPK1TDP1L3MBTL1
	SCHEMBL26811444	0.78	HTR2A (0.62)	SGMS2MAPTMAPK1TDP1L3MBTL1
	SCHEMBL12907163	0.76	CDK5 (0.49)	SGMS2DCPSHTTSMN1; SMN2MAPK14
	SCHEMBL26811294	0.76	SGMS2 (0.49)	SGMS2MAPTMAPK1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.