⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022494 | 0.76 | HTR2C (0.46) | — | |
| SCHEMBL23497964 | 0.76 | NOS3 (0.33) | — | |
| SCHEMBL7532560 | 0.76 | NOS3 (0.33) | — | |
| SCHEMBL11429258 | 0.69 | CA12 (0.50) | — | |
| SCHEMBL29546867 | 0.67 | TRPA1 (0.41) | — | |
| SCHEMBL153781 | 0.67 | CD44 (0.41) | — | |
| SCHEMBL1398081 | 0.67 | TRPA1 (0.41) | — | |
| Water SCHEMBL28834494 | 0.65 | TRPA1 (0.39) | — | |
| SCHEMBL789571 | 0.65 | NOS3 (0.32) | — | |
| SCHEMBL1202357 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2561 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | claimed |
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | claimed |
| WO-2024067783-A1 | PHOSPHORUS-CONTAINING COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海济煜医药科技有限公司 | 2024-04-04 | — | — | WO | claimed |
| US-20240101546-A1 | HETEROARYL-ACETYLENES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | EUBULUS BIOTHERAPEUTICS INC (CN) | 2024-03-28 | — | — | US | claimed |
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | claimed |
| WO-2023230179-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND TREATING CANCER | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-11-30 | — | — | WO | claimed |
| US-11802111-B2 | Cyclobutyl amide monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-31 | — | — | US | claimed |
| US-20230331725-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. | 2023-10-19 | — | — | US | claimed |
| EP-3969446-B1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2023-09-27 | — | — | EP | claimed |
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-1118781-A | Heterocyclic compound with activity against diabetes and preparation and application of same | MITSUTAKA CO LTD (JP) | 1996-03-20 | — | — | CN | claimed |
| EP-0462831-B1 | Bicyclic pyran derivatives and their use as inhibitors of 5-lipoxygenase | ZENECA LTD (GB) | 1996-02-28 | — | — | EP | claimed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | claimed |
| US-5362617-A | Multilayer element of support with color couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-08 | — | — | US | claimed |
| EP-0570006-A1 | A silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-18 | — | — | EP | claimed |
| CN-1064864-A | The tetraline that replaces and the preparation method of allied compound | PFIZER (US) | 1992-09-30 | — | — | CN | claimed |
| CN-1063489-A | Substituted benzotetrahydropyridines and related compounds | PFIZER (US) | 1992-08-12 | — | — | CN | claimed |
| EP-0462831-A2 | Bicyclic pyran derivatives and their use as inhibitors of 5-lipoxygenase | ZENECA LIMITED (GB) | 1991-12-27 | — | — | EP | claimed |
| CN-1032659-A | Substituted tetralins, chromans and like compounds for the treatment of asthma, arthritis and like diseases | PFIZER (US) | 1989-05-03 | — | — | CN | claimed |
| US-4091210-A | Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-05-23 | — | — | US | claimed |