SCHEMBL20049181

SCHEMBL20049181

CCCCC(CC)CN1C(=O)C2=C(c3ccc(-c4ccc(-c5ccc(C6=C7C(=O)N(CC(CC)CCCC)C(c8ccc(Br)s8)=C7C(=O)N6CC(CC)CCCC)s5)s4)s3)N(CC(CC)CCCC)C(=O)C2=C1c1ccc(C)s1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
HSF1 Q00613 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23011267 0.96 KDM4E (0.38) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL18066971 0.95 KMT2A (0.39) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL1689980 0.94 ALDH1A1 (0.42) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL793158 0.92 ALDH1A1 (0.40) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL25451106 0.91 ALDH1A1 (0.43) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL18985153 0.90 KMT2A (0.39) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL13569619 0.88 KDM4E (0.38) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL20724780 0.88 ALDH1A1 (0.38) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL12913126 0.88 KDM4E (0.35) KDM4EALDH1A1THRBHPGDKMT2A
SCHEMBL18328003 0.88 KDM4E (0.37) KDM4EALDH1A1THRBHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064937-A9 SINGLE MOLECULE AND ORGANIC SOLAR CELL COMPRISING SAME 주식회사 엘지화학 2018-04-12 WO disclosed