Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793158 | 0.95 | ALDH1A1 (0.40) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL18985153 | 0.93 | KMT2A (0.39) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL18066971 | 0.93 | KMT2A (0.39) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL13569619 | 0.91 | KDM4E (0.38) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL12913126 | 0.91 | KDM4E (0.35) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL15979470 | 0.90 | KDM4E (0.37) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL23011267 | 0.88 | KDM4E (0.38) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL20049181 | 0.88 | KDM4E (0.38) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL2457751 | 0.87 | KDM4E (0.33) | ALDH1A1KDM4ETHRBHPGDKMT2A | |
| SCHEMBL17264084 | 0.87 | KDM4E (0.33) | ALDH1A1KDM4ETHRBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202508-B2 | Dye compounds | MERCK PATENT GMBH (DE) | 2019-02-12 | — | — | US | disclosed |